Gilteritinib (Standard), 99.60%
cas: 1254053-43-4 — see every product listed under this CAS number, including other names
Gilteritinib (Standard), 99.60% (CAS 1254053-43-4) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 50 mg, 25 mg, 5 mg, 10 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-12432R-100 mg |
| cas | 1254053-43-4 |
| size | 100 mg |
| availability | In stock |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 100 mg | 5567.41 Pln | |
| MedChemExpress | 50 mg | 4007.03 Pln | |
| MedChemExpress | 25 mg | 2711.35 Pln | |
| MedChemExpress | 5 mg | 1081.31 Pln | |
| MedChemExpress | 10 mg | 1559.64 Pln |
properties
| delivery time | 2-3 weeks |
|---|---|
| purity | 99.60% |
Gilteritinib is a member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a primary carboxamide, a monomethoxybenzene, a member of piperidines, an aromatic amine, a member of pyrazines, a N-methylpiperazine, a member of oxanes and a secondary amino compound.
Source: ChEBI
| Molecular formula | C29H44N8O3 |
|---|---|
| Molecular weight | 552.7 g/mol |
| IUPAC name | 6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide |
| InChIKey | GYQYAJJFPNQOOW-UHFFFAOYSA-N |
| SMILES | CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5 |
Computed by PubChem (NCBI)