Gilteritinib, 98%

cas: 1254053-43-4 — see every product listed under this CAS number, including other names

Gilteritinib, 98% (CAS 1254053-43-4) is a chemical reagent available from Chemat. Available pack sizes: 100MG. Offered by: Thermo Scientific (Acros).

brandThermo Scientific (Acros)
catalog number474651000
cas1254053-43-4
size100MG
availability availability
Documents: Safety Data Sheet (MSDS)
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Thermo Scientific (Acros) 100MG 1069.07 Pln

properties

delivery time2-3 weeks
categoryChemicals
purity98%
Structural formula: {0} (CAS {1})

Gilteritinib is a member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a primary carboxamide, a monomethoxybenzene, a member of piperidines, an aromatic amine, a member of pyrazines, a N-methylpiperazine, a member of oxanes and a secondary amino compound.

Source: ChEBI

Identity
Molecular formulaC29H44N8O3
Molecular weight552.7 g/mol
IUPAC name6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
InChIKeyGYQYAJJFPNQOOW-UHFFFAOYSA-N
SMILESCCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5

Computed by PubChem (NCBI)

Synonyms: Gilteritinib, gilteritinibum, Gilteritinib HCl, Gilteritinib [USAN:INN], Gilteritinib (Standard), GILTERITINIB [MI], Gilteritinib(ASP2215), Gilteritinib (USAN/INN), GILTERITINIB [INN], GILTERITINIB [USAN]
Related forms of this compound
6-ethyl-3-[3-methoxy-4-[4-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide C29H44N8O3

Also listed as

6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide, 97%, 97% Chemat CAS 1254053-43-4
Gilteritinib Chemat Brand CAS 1254053-43-4
Gilteritinib, >95% (HPLC) TRC CAS 1254053-43-4
Gilteritinib/ 99.72% (existing batch purity) TargetMol CAS 1254053-43-4
Gilteritinib 97% Ambeed CAS 1254053-43-4
Gilteritinib, 99.84% MedChemExpress CAS 1254053-43-4
Gilteritinib (Standard), 99.60% MedChemExpress CAS 1254053-43-4
Gilteritinib, 97% Fluorochem CAS 1254053-43-4