Gilteritinib, 99.84%

cas: 1254053-43-4 — see every product listed under this CAS number, including other names

Gilteritinib, 99.84% (CAS 1254053-43-4) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 5 mg, 200 mg, 25 mg, 50 mg, 10 mg. Offered by: MedChemExpress.

brand	MedChemExpress
catalog number	HY-12432-100 mg
cas	1254053-43-4
size	100 mg
availability	In stock

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Available pack sizes

brand	size	price
MedChemExpress	100 mg	2757.79 Pln
MedChemExpress	5 mg	598.33 Pln
MedChemExpress	200 mg	3955.94 Pln
MedChemExpress	25 mg	1318.15 Pln
MedChemExpress	50 mg	1801.13 Pln
MedChemExpress	10 mg	839.82 Pln

properties

delivery time	1-2 weeks
purity	99.84%

Gilteritinib is a member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a primary carboxamide, a monomethoxybenzene, a member of piperidines, an aromatic amine, a member of pyrazines, a N-methylpiperazine, a member of oxanes and a secondary amino compound.

Source: ChEBI

Identity
Molecular formula	C₂₉H₄₄N₈O₃
Molecular weight	552.7 g/mol
IUPAC name	6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
InChIKey	GYQYAJJFPNQOOW-UHFFFAOYSA-N
SMILES	CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5

Computed by PubChem (NCBI)

Synonyms: Gilteritinib, gilteritinibum, Gilteritinib HCl, Gilteritinib [USAN:INN], Gilteritinib (Standard), GILTERITINIB [MI], Gilteritinib(ASP2215), Gilteritinib (USAN/INN), GILTERITINIB [INN], GILTERITINIB [USAN]