Gilteritinib, 97%
cas: 1254053-43-4 — see every product listed under this CAS number, including other names
Gilteritinib, 97% (CAS 1254053-43-4) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 50mg, 100mg, 250mg, 1g. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F799808-5MG |
| cas | 1254053-43-4 |
| size | 5mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 5mg | 289.50 Pln | |
| Fluorochem | 50mg | 362.39 Pln | |
| Fluorochem | 100mg | 513.38 Pln | |
| Fluorochem | 250mg | 825.77 Pln | |
| Fluorochem | 1g | 1804.59 Pln |
properties
| purity | 97% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Gilteritinib is a member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a primary carboxamide, a monomethoxybenzene, a member of piperidines, an aromatic amine, a member of pyrazines, a N-methylpiperazine, a member of oxanes and a secondary amino compound.
Source: ChEBI
| Molecular formula | C29H44N8O3 |
|---|---|
| Molecular weight | 552.7 g/mol |
| IUPAC name | 6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide |
| InChIKey | GYQYAJJFPNQOOW-UHFFFAOYSA-N |
| SMILES | CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5 |
Computed by PubChem (NCBI)