Products 96206-92-7
CAS 96206-92-7 appears in our catalog under these names: Mpep, 95%, MPEP, MPEP/ 99.31% (existing batch purity), 2-Methyl-6-(phenylethynyl)pyridine, >98.0%(GC), MPEP 98%. Offered by: Combi-blocks, GLPBio, TargetMol, TCI, Biosynth. Available pack sizes: 10g, 5g, 250mg, 1g, 10mg, 100mg, 25mg, 5mg.
MPEP/ 99.31% (existing batch purity)
TargetMol- size: 10mg, 25mg, 50mg, 100mg
- Variants: 6
from 452.11
2-methyl-6-(phenylethynyl)pyridine is a methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. It has a role as an anxiolytic drug and a metabotropic glutamate receptor antagonist. It is a member of methylpyridines and an acetylenic compound. It is a conjugate base of a 2-methyl-6-(phenylethynyl)pyridinium(1+). It derives from a hydride of an acetylene.
Source: ChEBI
| Molecular formula | C14H11N |
|---|---|
| Molecular weight | 193.24 g/mol |
| IUPAC name | 2-methyl-6-(2-phenylethynyl)pyridine |
| InChIKey | NEWKHUASLBMWRE-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C#CC2=CC=CC=C2 |
Computed by PubChem (NCBI)