Teriflunomide, >98.0%(GC)

cas: 163451-81-8 — see every product listed under this CAS number, including other names

Teriflunomide, >98.0%(GC) (CAS 163451-81-8) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 1g. Offered by: TCI.

brandTCI
catalog numberT3287-100MG
cas163451-81-8
size100mg
availability 2 tygodnie|2 weeks
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
TCI 100mg 211.77 Pln
TCI 1g 1209.97 Pln

properties

delivery time2 weeks
categorychemicals
purity>98.0%(GC)
Structural formula: {0} (CAS {1})

Teriflunomide is an enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, a tyrosine kinase inhibitor, a drug metabolite, a hepatotoxic agent and an EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor. It is a secondary carboxamide, a nitrile, an enol, an enamide, an aromatic amide and a member of (trifluoromethyl)benzenes.

Source: ChEBI

Identity
Molecular formulaC12H9F3N2O2
Molecular weight270.21 g/mol
IUPAC name(Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
InChIKeyUTNUDOFZCWSZMS-YFHOEESVSA-N
SMILESC/C(=C(\C#N)/C(=O)NC1=CC=C(C=C1)C(F)(F)F)/O

Computed by PubChem (NCBI)

Synonyms: Teriflunomide, Aubagio, Flucyamide, (Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide, teriflunomida, teriflunomidum, (Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide, (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide, N-(4-Trifluoromethylphenyl)-2-cyano-2-hydroxycrotonamide, 2-hydroxyethylidene-cyanoacetic acid-4-trifluoromethyl anilide
Related forms of this compound
(E)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide C12H9F3N2O2
2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide C12H9F3N2O2
(Z)-2-cyano-3-hydroxy-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]but-2-enamide C12H9F3N2O2
Isomers (same molecular formula)
4-(3-methylpyrazol-1-yl)-2-(trifluoromethyl)benzoic acid C12H9F3N2O2
4-[[3-(trifluoromethyl)pyrazol-1-yl]methyl]benzoic acid C12H9F3N2O2
3-[[3-(trifluoromethyl)pyrazol-1-yl]methyl]benzoic acid C12H9F3N2O2
3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)benzoic acid C12H9F3N2O2
2-[3-[3-(trifluoromethyl)phenyl]pyrazol-1-yl]acetic acid C12H9F3N2O2
3-[[3-(trifluoromethyl)phenyl]methyl]imidazole-4-carboxylic acid C12H9F3N2O2
1-[[4-(trifluoromethyl)phenyl]methyl]pyrazole-4-carboxylic acid C12H9F3N2O2
3-[[4-(trifluoromethyl)phenyl]methyl]imidazole-4-carboxylic acid C12H9F3N2O2
1-[[2-(trifluoromethyl)phenyl]methyl]pyrazole-4-carboxylic acid C12H9F3N2O2

Also listed as

Leflunomide EP Impurity B (Teriflunomide) Chemat Brand CAS 163451-81-8
A 77-1726, >95% (HPLC) TRC CAS 163451-81-8
Teriflunomide, >95% (HPLC) TRC CAS 163451-81-8
(2Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide (Teriflunomide) Mikromol CAS 163451-81-8
A–771726 GLPBio CAS 163451-81-8
Teriflunomide/ 99.95% (existing batch purity) TargetMol CAS 163451-81-8
Teriflunomide Biosynth CAS 163451-81-8
Teriflunomide 98% Ambeed CAS 163451-81-8
(2Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide, 98%, 98% Chemat CAS 163451-81-8
Teriflunomide, 99.92% MedChemExpress CAS 163451-81-8
Teriflunomide (Standard) MedChemExpress CAS 163451-81-8
Teriflunomide, 95% Fluorochem CAS 163451-81-8