Teriflunomide

cas: 163451-81-8 — see every product listed under this CAS number, including other names

Teriflunomide (CAS 163451-81-8) is a chemical reagent available from Chemat. Available pack sizes: 10g, 1g, 0,5g, 5g, 250MG, 2g, 25g, 100g. Offered by: Biosynth, Thermo Scientific (Acros), Sigma-Aldrich.

brandBiosynth
catalog numberJ-010046-10g
cas163451-81-8
size10g
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Available pack sizes

brand size price
Biosynth 10g price on request
Biosynth 1g price on request
Biosynth 0,5g price on request
Biosynth 5g price on request
Thermo Scientific (Acros) 1g 1322.97 Pln
Thermo Scientific (Acros) 250MG 458.81 Pln
Biosynth 2g price on request
Biosynth 25g price on request
Biosynth 5g price on request
Biosynth 10g price on request
Biosynth 100g price on request
Biosynth 50g price on request
Sigma-Aldrich 100MG 3628.00 Pln

properties

categoryControlled Products
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

Teriflunomide is an enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, a tyrosine kinase inhibitor, a drug metabolite, a hepatotoxic agent and an EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor. It is a secondary carboxamide, a nitrile, an enol, an enamide, an aromatic amide and a member of (trifluoromethyl)benzenes.

Source: ChEBI

Identity
Molecular formulaC12H9F3N2O2
Molecular weight270.21 g/mol
IUPAC name(Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
InChIKeyUTNUDOFZCWSZMS-YFHOEESVSA-N
SMILESC/C(=C(\C#N)/C(=O)NC1=CC=C(C=C1)C(F)(F)F)/O

Computed by PubChem (NCBI)

Synonyms: Teriflunomide, Aubagio, Flucyamide, (Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide, teriflunomida, teriflunomidum, (Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide, (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide, N-(4-Trifluoromethylphenyl)-2-cyano-2-hydroxycrotonamide, 2-hydroxyethylidene-cyanoacetic acid-4-trifluoromethyl anilide
Related forms of this compound
(E)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide C12H9F3N2O2
2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide C12H9F3N2O2
(Z)-2-cyano-3-hydroxy-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]but-2-enamide C12H9F3N2O2
Isomers (same molecular formula)
4-(3-methylpyrazol-1-yl)-2-(trifluoromethyl)benzoic acid C12H9F3N2O2
4-[[3-(trifluoromethyl)pyrazol-1-yl]methyl]benzoic acid C12H9F3N2O2
3-[[3-(trifluoromethyl)pyrazol-1-yl]methyl]benzoic acid C12H9F3N2O2
3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)benzoic acid C12H9F3N2O2
2-[3-[3-(trifluoromethyl)phenyl]pyrazol-1-yl]acetic acid C12H9F3N2O2
3-[[3-(trifluoromethyl)phenyl]methyl]imidazole-4-carboxylic acid C12H9F3N2O2
1-[[4-(trifluoromethyl)phenyl]methyl]pyrazole-4-carboxylic acid C12H9F3N2O2
3-[[4-(trifluoromethyl)phenyl]methyl]imidazole-4-carboxylic acid C12H9F3N2O2
1-[[2-(trifluoromethyl)phenyl]methyl]pyrazole-4-carboxylic acid C12H9F3N2O2

Also listed as

Leflunomide EP Impurity B (Teriflunomide) Chemat Brand CAS 163451-81-8
A 77-1726, >95% (HPLC) TRC CAS 163451-81-8
Teriflunomide, >95% (HPLC) TRC CAS 163451-81-8
(2Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide (Teriflunomide) Mikromol CAS 163451-81-8
A–771726 GLPBio CAS 163451-81-8
Teriflunomide/ 99.95% (existing batch purity) TargetMol CAS 163451-81-8
Teriflunomide, >98.0%(GC) TCI CAS 163451-81-8
Teriflunomide 98% Ambeed CAS 163451-81-8
(2Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide, 98%, 98% Chemat CAS 163451-81-8
Teriflunomide, 99.92% MedChemExpress CAS 163451-81-8
Teriflunomide (Standard) MedChemExpress CAS 163451-81-8
Teriflunomide, 95% Fluorochem CAS 163451-81-8