Products 1252003-15-8
CAS 1252003-15-8 appears in our catalog under these names: Tubastatin A/ 98.36% (existing batch purity), Tubastatin A, Tubastatin A, Tubastatin A, 99.07%, Tubastatin A (Standard). Offered by: TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 10mg, 25mg, 50mg, 100mg, 200mg, 500mg, 2000mg, 10mM (in 1ml dmso).
Tubastatin A is a pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminocarbonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). It has a role as an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a hydroxamic acid, a pyridoindole and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C20H21N3O2 |
|---|---|
| Molecular weight | 335.4 g/mol |
| IUPAC name | N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide |
| InChIKey | GOVYBPLHWIEHEJ-UHFFFAOYSA-N |
| SMILES | CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO |
Computed by PubChem (NCBI)
Synonyms:
Tubastatin A, Tubastatin-A, N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide, N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido(4,3-b)indol-5-yl)methyl)benzamide, Tubastatin A BASE, Tubastatin A (free base), Tubastatin A(free base), 1252003-15-8 (free base), Tubastatin A Trifluoroacetic Acid Salt, Tubastatin A (trifluoroacetate)