CAS 28860-95-9 appears in our catalog under these names: Carbidopa, (S)-(-)-Carbidopa, Carbidopa/ min. 98%, S-(-)-CARBIDOPA, Carbidopa, 99% (LCMS), 99% (LCMS). Offered by: Chemat Brand, TRC, GLPBio, TargetMol, Sigma-Aldrich. Available pack sizes: on request, 100mg, 1g, 25mg, 10mM (in 1ml dmso), 5mg, 10mg, 50mg.
Carbidopa (anhydrous) is 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa. It has a role as an antiparkinson drug, a dopaminergic agent and an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. It is a member of hydrazines, a monocarboxylic acid and a member of catechols.
Source: ChEBI
| Molecular formula | C10H14N2O4 |
|---|---|
| Molecular weight | 226.23 g/mol |
| IUPAC name | (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid |
| InChIKey | TZFNLOMSOLWIDK-JTQLQIEISA-N |
| SMILES | C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN |
Computed by PubChem (NCBI)