Products 55481-88-4
CAS 55481-88-4 appears in our catalog under these names: Mollugin, 95%, Mollugin, Mollugin/ 98%, Mollugin, >98.0%(HPLC), Mollugin 98+%. Offered by: Combi-blocks, TRC, GLPBio, TargetMol, TCI. Available pack sizes: 10mg, 50mg, 100mg, 1g, 20mg, 5mg, 25mg, 500mg.
Rubimaillin is a benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-B activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme. It has a role as an antineoplastic agent, a neuroprotective agent, an acyl-CoA:cholesterol acyltransferase 2 inhibitor, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and a plant metabolite. It is a methyl ester, a member of phenols and a benzochromene.
Source: ChEBI
| Molecular formula | C17H16O4 |
|---|---|
| Molecular weight | 284.31 g/mol |
| IUPAC name | methyl 6-hydroxy-2,2-dimethylbenzo[h]chromene-5-carboxylate |
| InChIKey | VLGATXOTCNBWIT-UHFFFAOYSA-N |
| SMILES | CC1(C=CC2=C(O1)C3=CC=CC=C3C(=C2C(=O)OC)O)C |
Computed by PubChem (NCBI)
Synonyms:
Mollugin, Rubimaillin, methyl 6-hydroxy-2,2-dimethylbenzo[h]chromene-5-carboxylate, 2H-Naphtho(1,2-b)pyran-5-carboxylic acid, 6-hydroxy-2,2-dimethyl-, methyl ester, methyl 6-hydroxy-2,2-dimethylbenzo(h)chromene-5-carboxylate, Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate, methyl 6-hydroxy-2,2-dimethyl-benzo[h]chromene-5-carboxylate, Rubimailin, Mollugin?, VLGATXOTCNBWIT-UHFFFAOYSA-N