Products 66635-92-5
CAS 66635-92-5 appears in our catalog under these names: (S)–Ketorolac, (S)-Ketorolac, (S)-Ketorolac, >95% (HPLC), (S)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, ≥98%, ≥98%, (S)-Ketorolac, 99.27%. Offered by: GLPBio, Chemat Brand, TRC, TargetMol, Chemat. Available pack sizes: 5mg, on request, 10mg, 2mg, 1mg, 25mg, 25 mg, 10mM/1mL.
(S)-ketorolac is a 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. It is an enantiomer of a (R)-ketorolac.
Source: ChEBI
| Molecular formula | C15H13NO3 |
|---|---|
| Molecular weight | 255.27 g/mol |
| IUPAC name | (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid |
| InChIKey | OZWKMVRBQXNZKK-NSHDSACASA-N |
| SMILES | C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)[C@H]1C(=O)O |
Computed by PubChem (NCBI)
Synonyms:
(S)-Ketorolac, (-)-Ketorolac, Ketorolac, (S)-, S-(-)-Ketorolac, (S)-(-)-ketorolac, 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1S)-, (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, (S)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, 1H-Pyrrolizine-1-carboxylicacid, 5-benzoyl-2,3-dihydro-, (1S)-, 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (S)-