CAS 84692-91-1 appears in our catalog under these names: Arglabin/ 99.62% (existing batch purity), Arglabin, Arglabin, >98.0%(HPLC), Arglabin, 98.00%, Arglabin, 98%, 98%. Offered by: TargetMol, Biosynth, TCI, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10 mg, 10mM/1mL.
Arglabin is an organic heterotetracyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-dimethyl-1,3a,4,5,6,7-hexahydroazulen-5-yl group in which the double bond in the 7-membered ring has been epoxidised and in which the hydroxy group and the carboxy group have undergone formal condensation to give the corresponding gamma-lactone. It is found in Artemisia glabella. Arglabin-DMA HCl, the hydrochloride salt of the adduct resulting from the conjugate addition of dimethylamine to the ene-lactone moiety, has been successfully used in Khazakhstan for the treatment of breast, colon, ovarian and lung cancers. It has a role as a metabolite and an antineoplastic agent. It is an epoxide, a gamma-lactone, a sesquiterpene lactone and an organic heterotetracyclic compound.
Source: ChEBI
| Molecular formula | C15H18O3 |
|---|---|
| Molecular weight | 246.30 g/mol |
| IUPAC name | (1R,3S,6S,10S,11R)-3,12-dimethyl-7-methylidene-2,9-dioxatetracyclo[9.3.0.01,3.06,10]tetradec-12-en-8-one |
| InChIKey | UVJYAKBJSGRTHA-CUZKYEQNSA-N |
| SMILES | CC1=CC[C@@]23[C@H]1[C@@H]4[C@@H](CC[C@@]2(O3)C)C(=C)C(=O)O4 |
Computed by PubChem (NCBI)