Products 873054-44-5

CAS 873054-44-5 appears in our catalog under these names: Ivacaftor, Ivacaftor, >95% (HPLC), Ivacaftor/ 99.98% (existing batch purity), Ivacaftor (VX–770), Ivacaftor, 98.00%. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 100mg, 500mg, 5g, 250mg, 1mg, 5mg, 10mg.

Ivacaftor
Chemat Brand, Mikromol, Biosynth
  • size: on request, 250mg, 0,025g, 0,05g
  • Variants: 7
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Ivacaftor, >95% (HPLC)
TRC
  • size: 100mg, 500mg, 5g
  • Variants: 3
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Ivacaftor/ 99.98% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 399.00
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Ivacaftor (VX–770)
GLPBio
  • size: 10mg, 100mg, 25mg, 50mg
  • Variants: 5
from 578.32
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Ivacaftor, 98.00%
Chemat
  • size: 250mg
  • Variants: 1
from 699.52
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Ivacaftor 97%
Ambeed
  • size: 100g, 1mg, 5mg, 10mg
  • Variants: 9
from 120.06
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N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide, 97%, 97%
Chemat
  • size: 5mg, 10mg, 100mg, 250mg
  • Variants: 8
from 78.80
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Ivacaftor, 99.97%
MedChemExpress
  • size: 5 mg, 10mM/1mL, 100 mg, 10 mg
  • Variants: 6
from 561.18
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Ivacaftor (Standard)
MedChemExpress
  • size: 25 mg, 50 mg, 10 mg, 5 mg
  • Variants: 5
from 1081.31
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IVACAFTOR, 98%
Fluorochem
  • size: 250mg, 1g, 5g
  • Variants: 3
from 404.04
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Ivacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis. It has a role as a CFTR potentiator and an orphan drug. It is a quinolone, a monocarboxylic acid amide, a member of phenols and an aromatic amide.

Source: ChEBI

Identity
Molecular formulaC24H28N2O3
Molecular weight392.5 g/mol
IUPAC nameN-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
InChIKeyPURKAOJPTOLRMP-UHFFFAOYSA-N
SMILESCC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C

Computed by PubChem (NCBI)

Synonyms: Ivacaftor, Kalydeco, N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide, ivacaftorum, ORKAMBI COMPONENT IVACAFTOR, SYMKEVI COMPONENT IVACAFTOR, TRIKAFTA COMPONENT IVACAFTOR, Elexacaftor, Tezacaftor, and Ivacaftor, Ivacaftor (VX-770), Ivacaftor-d18
Related forms of this compound
N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide C24H28N2O3
N-[2-tert-butyl-4-[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]-5-hydroxyphenyl]-4-oxo-1H-quinoline-3-carboxamide C24H28N2O3
Isomers (same molecular formula)
5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one C24H28N2O3
1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol C24H28N2O3
1,1-bis[4-(4,4-dimethyl-5H-1,3-oxazol-2-yl)phenyl]ethanol C24H28N2O3
N,N-diethyl-3-hydroxy-4-spiro[chromene-2,4'-piperidine]-4-ylbenzamide C24H28N2O3
N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide C24H28N2O3
4-[2-(1-ethyl-5-oxo-4,4-diphenylpyrrolidin-3-yl)ethyl]morpholin-3-one C24H28N2O3
5-[(1R)-2-[[5-ethyl-6-(2,2,2-trideuterioethyl)-2,3-dihydro-1H-inden-2-yl]amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one C24H28N2O3
(2S)-2-[[4-(2-cyanophenyl)phenyl]methyl-pentanoylamino]-3-methylbutanoic acid C24H28N2O3
N-(3,5-ditert-butyl-2-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide C24H28N2O3
(5-amino-2,4-ditert-butylphenyl) 4-oxo-1H-quinoline-3-carboxylate C24H28N2O3