cas: 941678-49-5 — see every product listed under this CAS number, including other names
(βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile, 98% (CAS 941678-49-5) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 50mg, 100mg, 250mg, 1g, 5g. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch11461P-1mg |
| cas | 941678-49-5 |
| size | 1mg |
| availability | 10g |
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| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 88.40 Pln | |
| Chemat | 10mg | 117.20 Pln | |
| Chemat | 50mg | 165.20 Pln | |
| Chemat | 100mg | 165.20 Pln | |
| Chemat | 250mg | 270.80 Pln | |
| Chemat | 1g | 683.60 Pln | |
| Chemat | 5g | 2128.40 Pln |
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
Ruxolitinib is a pyrazole substituted at position 1 by a 2-cyano-1-cyclopentylethyl group and at position 3 by a pyrrolo[2,3-d]pyrimidin-4-yl group. Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a nitrile, a member of pyrazoles and a pyrrolopyrimidine.
Source: ChEBI
| Molecular formula | C17H18N6 |
|---|---|
| Molecular weight | 306.4 g/mol |
| IUPAC name | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile |
| InChIKey | HFNKQEVNSGCOJV-OAHLLOKOSA-N |
| SMILES | C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
Computed by PubChem (NCBI)