cas: 941678-49-5 — see every product listed under this CAS number, including other names
Ruxolitinib (Standard), 99.74% (CAS 941678-49-5) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 25 mg, 5 mg, 10 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-50856R-100 mg |
| cas | 941678-49-5 |
| size | 100 mg |
| availability | In stock |
Ask us about this product — we're happy to help.
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 100 mg | 3765.54 Pln | |
| MedChemExpress | 25 mg | 1982.24 Pln | |
| MedChemExpress | 5 mg | 811.96 Pln | |
| MedChemExpress | 10 mg | 1155.61 Pln | |
| MedChemExpress | 50 mg | 2734.57 Pln |
| delivery time | 2-3 weeks |
|---|---|
| purity | 99.74% |
Ruxolitinib is a pyrazole substituted at position 1 by a 2-cyano-1-cyclopentylethyl group and at position 3 by a pyrrolo[2,3-d]pyrimidin-4-yl group. Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a nitrile, a member of pyrazoles and a pyrrolopyrimidine.
Source: ChEBI
| Molecular formula | C17H18N6 |
|---|---|
| Molecular weight | 306.4 g/mol |
| IUPAC name | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile |
| InChIKey | HFNKQEVNSGCOJV-OAHLLOKOSA-N |
| SMILES | C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
Computed by PubChem (NCBI)