cas: 941678-49-5 — see every product listed under this CAS number, including other names
Ruxolitinib (CAS 941678-49-5) is a chemical reagent available from Chemat. Available pack sizes: on request, 50mg, 1g, 0,5g, 2g, 5g, 10g. Offered by: Chemat Brand, Mikromol, Biosynth.
| brand | Chemat Brand |
|---|---|
| catalog number | AO-R0067.00 |
| cas | 941678-49-5 |
| size | on request |
| availability | In stock |
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| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Chemat Brand | on request | price on request | |
| Mikromol | 50mg | price on request | |
| Biosynth | 1g | price on request | |
| Biosynth | 0,5g | price on request | |
| Biosynth | 2g | price on request | |
| Biosynth | 5g | price on request | |
| Biosynth | 10g | price on request |
| delivery time | To be confirmed by Chemat |
|---|---|
| purity | No data |
Ruxolitinib is a pyrazole substituted at position 1 by a 2-cyano-1-cyclopentylethyl group and at position 3 by a pyrrolo[2,3-d]pyrimidin-4-yl group. Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a nitrile, a member of pyrazoles and a pyrrolopyrimidine.
Source: ChEBI
| Molecular formula | C17H18N6 |
|---|---|
| Molecular weight | 306.4 g/mol |
| IUPAC name | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile |
| InChIKey | HFNKQEVNSGCOJV-OAHLLOKOSA-N |
| SMILES | C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
Computed by PubChem (NCBI)