(S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, 95%

cas: 1038915-60-4 — see every product listed under this CAS number, including other names

(S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, 95% (CAS 1038915-60-4) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 1g. Offered by: Fluorochem.

brandFluorochem
catalog numberF227536-250MG
cas1038915-60-4
size250mg
availability In Stock China
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Fluorochem 250mg 549.82 Pln
Fluorochem 1g 1013.20 Pln

properties

purity95,00%
dual useNo
currencyEUR
delivery time3-4 weeks
categoryOdczynniki chemiczne

Niraparib is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has S-configuration. It is a potent inhibitor of PARP1 and PARP2 (IC50 of 3.8 and 2.1 nM, respectively) and approved as a first-line maintenance treatment for women with advanced ovarian cancer after responding to platinum-based chemotherapy. It has a role as a radiosensitizing agent, an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis inducer.

Source: ChEBI

Identity
Molecular formulaC19H20N4O
Molecular weight320.4 g/mol
IUPAC name2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide
InChIKeyPCHKPVIQAHNQLW-CQSZACIVSA-N
SMILESC1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N

Computed by PubChem (NCBI)

Synonyms: Niraparib, 2-{4-[(3s)-piperidin-3-yl]phenyl}-2h-indazole-7-carboxamide, 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide, niraparibum, 2-(4-((3S)-piperidin-3-yl)phenyl)indazole-7-carboxamide, (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, Niraparib [USAN], 2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide, Niraparib (USAN), 2-[4-[(3S)-3-Piperidyl]phenyl]indazole-7-carboxamide
Related forms of this compound
2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide C19H20N4O
2-[4-[(3R)-piperidin-3-yl]phenyl]indazole-7-carboxamide C19H20N4O
Isomers (same molecular formula)
1-[(4-aminophenyl)methyl]-N-(3,5-dimethylphenyl)imidazole-4-carboxamide C19H20N4O
1-[(4-aminophenyl)methyl]-N-(2,4-dimethylphenyl)imidazole-4-carboxamide C19H20N4O
1-[(4-aminophenyl)methyl]-N-(4-ethylphenyl)imidazole-4-carboxamide C19H20N4O
[1-(1-benzhydrylazetidin-3-yl)triazol-4-yl]methanol C19H20N4O
9,9-dimethyl-6-pyridin-3-yl-6,8,10,11-tetrahydro-5H-pyrido[3,2-b][1,4]benzodiazepin-7-one C19H20N4O
1-hydroxy-4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazole C19H20N4O
1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-amine C19H20N4O
5-[6-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]pyridazin-3-yl]-1H-indole C19H20N4O
4-(1H-indol-4-yl)-N-phenylpiperazine-1-carboxamide C19H20N4O
2-[4-[(dimethylamino)methyl]phenyl]-1,3,10-triazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-9-one C19H20N4O

Also listed as

Niraparib Chemat Brand CAS 1038915-60-4
Niraparib, >95% (HPLC) TRC CAS 1038915-60-4
Niraparib/ 99.85% (existing batch purity) TargetMol CAS 1038915-60-4
MK–4827 GLPBio CAS 1038915-60-4
MK 4827 Biosynth CAS 1038915-60-4
Niraparib, 97% Thermo Scientific (Acros) CAS 1038915-60-4
Niraparib, 99.96% MedChemExpress CAS 1038915-60-4
Niraparib (Standard) MedChemExpress CAS 1038915-60-4
2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide, 98% Chemat CAS 1038915-60-4
Niraparib-d4 Chemat Brand CAS 1038915-60-4 (non-labelled)

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