cas: 1038915-60-4 — see every product listed under this CAS number, including other names
Niraparib, 99.96% (CAS 1038915-60-4) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 25 mg, 100 mg, 10 mg, 10mM/1mL, 5 mg, 500 mg, 1 g. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-10619-50 mg |
| cas | 1038915-60-4 |
| size | 50 mg |
| availability | In stock |
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| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 983.78 Pln | |
| MedChemExpress | 25 mg | 793.38 Pln | |
| MedChemExpress | 100 mg | 1462.12 Pln | |
| MedChemExpress | 10 mg | 598.33 Pln | |
| MedChemExpress | 10mM/1mL | 491.52 Pln | |
| MedChemExpress | 5 mg | 454.37 Pln | |
| MedChemExpress | 500 mg | 3380.09 Pln | |
| MedChemExpress | 1 g | 5302.70 Pln |
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.96% |
Niraparib is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has S-configuration. It is a potent inhibitor of PARP1 and PARP2 (IC50 of 3.8 and 2.1 nM, respectively) and approved as a first-line maintenance treatment for women with advanced ovarian cancer after responding to platinum-based chemotherapy. It has a role as a radiosensitizing agent, an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis inducer.
Source: ChEBI
| Molecular formula | C19H20N4O |
|---|---|
| Molecular weight | 320.4 g/mol |
| IUPAC name | 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide |
| InChIKey | PCHKPVIQAHNQLW-CQSZACIVSA-N |
| SMILES | C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
Computed by PubChem (NCBI)