cas: 1038915-60-4 — see every product listed under this CAS number, including other names
2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide, 98% (CAS 1038915-60-4) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 50mg, 100mg, 250mg, 1g. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch1149ZU-1mg |
| cas | 1038915-60-4 |
| size | 1mg |
| availability | 35.85g |
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| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 88.40 Pln | |
| Chemat | 2mg | 93.20 Pln | |
| Chemat | 5mg | 98.00 Pln | |
| Chemat | 10mg | 107.60 Pln | |
| Chemat | 50mg | 198.80 Pln | |
| Chemat | 100mg | 203.60 Pln | |
| Chemat | 250mg | 338.00 Pln | |
| Chemat | 1g | 611.60 Pln | |
| Chemat | 5g | 1605.20 Pln | |
| Chemat | 10g | 2541.20 Pln |
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
Niraparib is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has S-configuration. It is a potent inhibitor of PARP1 and PARP2 (IC50 of 3.8 and 2.1 nM, respectively) and approved as a first-line maintenance treatment for women with advanced ovarian cancer after responding to platinum-based chemotherapy. It has a role as a radiosensitizing agent, an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis inducer.
Source: ChEBI
| Molecular formula | C19H20N4O |
|---|---|
| Molecular weight | 320.4 g/mol |
| IUPAC name | 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide |
| InChIKey | PCHKPVIQAHNQLW-CQSZACIVSA-N |
| SMILES | C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
Computed by PubChem (NCBI)