cas: 1038915-60-4 — see every product listed under this CAS number, including other names
MK–4827 (CAS 1038915-60-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC17802-10 |
| cas | 1038915-60-4 |
| size | 10mg |
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| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 859.15 Pln | |
| GLPBio | 100mg | 2899.85 Pln | |
| GLPBio | 5mg | 676.61 Pln | |
| GLPBio | 50mg | 2141.60 Pln |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Niraparib is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has S-configuration. It is a potent inhibitor of PARP1 and PARP2 (IC50 of 3.8 and 2.1 nM, respectively) and approved as a first-line maintenance treatment for women with advanced ovarian cancer after responding to platinum-based chemotherapy. It has a role as a radiosensitizing agent, an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis inducer.
Source: ChEBI
| Molecular formula | C19H20N4O |
|---|---|
| Molecular weight | 320.4 g/mol |
| IUPAC name | 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide |
| InChIKey | PCHKPVIQAHNQLW-CQSZACIVSA-N |
| SMILES | C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
Computed by PubChem (NCBI)