PF 06651600

cas: 1792180-81-4 — see every product listed under this CAS number, including other names

PF 06651600 (CAS 1792180-81-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 50mg. Offered by: Biosynth.

brandBiosynth
catalog numberBP168506-10mg
cas1792180-81-4
size10mg
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Available pack sizes

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Biosynth 50mg price on request

properties

categoryLife Sciences
purityNo data
delivery time3-4 Weeks
Structural formula: {0} (CAS {1})

Ritlecitinib is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a [(3R,6S)-6-methyl-1-(prop-2-enoyl)piperidin-3-yl]amino group. It is a dual inhibitor of Janus kinase 3 and the TEC family of tyrosine kinases. It has a role as an anti-inflammatory drug, an immunosuppressive agent, an antirheumatic drug, a dermatologic drug and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a tertiary carboxamide, a member of acrylamides, a pyrrolopyrimidine, a N-acylpiperidine and a secondary amino compound. It is a conjugate base of a ritlecitinib(1+).

Source: ChEBI

Identity
Molecular formulaC15H19N5O
Molecular weight285.34 g/mol
IUPAC name1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
InChIKeyCBRJPFGIXUFMTM-WDEREUQCSA-N
SMILESC[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3

Computed by PubChem (NCBI)

Synonyms: ritlecitinib, Ritlecitinib (PF-06651600), ritlecitinibum, Ritlecitinib [MI], RITLECITINIB [INN], RITLECITINIB [WHO-DD], orb1301838, example 5 [WO2015083028], compound 11 [PMID: 28139931]
Related forms of this compound
1-[(2R,5S)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one C15H19N5O
Isomers (same molecular formula)
(4-aminopiperidin-1-yl)-[1-(4-methylphenyl)triazol-4-yl]methanone C15H19N5O
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine oxide C15H19N5O
1-[2-cyclobutyl-7-[(E)-2-(dimethylamino)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethanone C15H19N5O
2-(4-methyl-6-oxo-1H-pyrimidin-2-yl)-1-(4-propan-2-ylphenyl)guanidine C15H19N5O
2-(4,6-dimethylpyrimidin-2-yl)-1-(2-ethoxyphenyl)guanidine C15H19N5O
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine oxide C15H19N5O
1-ethyl-6-methyl-4-(oxan-4-ylamino)pyrazolo[3,4-b]pyridine-5-carbonitrile C15H19N5O
2-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]acetamide C15H19N5O
4-N-(6-methyl-2-morpholin-4-ylpyrimidin-4-yl)benzene-1,4-diamine C15H19N5O

Also listed as

Ritlecitinib TRC CAS 1792180-81-4
Ritlecitinib/ 99.92% (existing batch purity) TargetMol CAS 1792180-81-4
PF–06651600 GLPBio CAS 1792180-81-4
Ritlecitinib, 99.80% MedChemExpress CAS 1792180-81-4
Ritlecitinib (Standard) MedChemExpress CAS 1792180-81-4
Ritlecitinib, 95% Fluorochem CAS 1792180-81-4