Ritlecitinib

cas: 1792180-81-4 — see every product listed under this CAS number, including other names

Ritlecitinib (CAS 1792180-81-4) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 10mg, 50mg. Offered by: TRC.

brandTRC
catalog numberTRC-R299810-100MG
cas1792180-81-4
size100mg
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Available pack sizes

brand size price
TRC 100mg price on request
TRC 10mg price on request
TRC 50mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Ritlecitinib is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a [(3R,6S)-6-methyl-1-(prop-2-enoyl)piperidin-3-yl]amino group. It is a dual inhibitor of Janus kinase 3 and the TEC family of tyrosine kinases. It has a role as an anti-inflammatory drug, an immunosuppressive agent, an antirheumatic drug, a dermatologic drug and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a tertiary carboxamide, a member of acrylamides, a pyrrolopyrimidine, a N-acylpiperidine and a secondary amino compound. It is a conjugate base of a ritlecitinib(1+).

Source: ChEBI

Identity
Molecular formulaC15H19N5O
Molecular weight285.34 g/mol
IUPAC name1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
InChIKeyCBRJPFGIXUFMTM-WDEREUQCSA-N
SMILESC[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3

Computed by PubChem (NCBI)

Synonyms: ritlecitinib, Ritlecitinib (PF-06651600), ritlecitinibum, Ritlecitinib [MI], RITLECITINIB [INN], RITLECITINIB [WHO-DD], orb1301838, example 5 [WO2015083028], compound 11 [PMID: 28139931]
Related forms of this compound
1-[(2R,5S)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one C15H19N5O
Isomers (same molecular formula)
(4-aminopiperidin-1-yl)-[1-(4-methylphenyl)triazol-4-yl]methanone C15H19N5O
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine oxide C15H19N5O
1-[2-cyclobutyl-7-[(E)-2-(dimethylamino)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethanone C15H19N5O
2-(4-methyl-6-oxo-1H-pyrimidin-2-yl)-1-(4-propan-2-ylphenyl)guanidine C15H19N5O
2-(4,6-dimethylpyrimidin-2-yl)-1-(2-ethoxyphenyl)guanidine C15H19N5O
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine oxide C15H19N5O
1-ethyl-6-methyl-4-(oxan-4-ylamino)pyrazolo[3,4-b]pyridine-5-carbonitrile C15H19N5O
2-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]acetamide C15H19N5O
4-N-(6-methyl-2-morpholin-4-ylpyrimidin-4-yl)benzene-1,4-diamine C15H19N5O

Also listed as

Ritlecitinib/ 99.92% (existing batch purity) TargetMol CAS 1792180-81-4
PF–06651600 GLPBio CAS 1792180-81-4
PF 06651600 Biosynth CAS 1792180-81-4
Ritlecitinib, 99.80% MedChemExpress CAS 1792180-81-4
Ritlecitinib (Standard) MedChemExpress CAS 1792180-81-4
Ritlecitinib, 95% Fluorochem CAS 1792180-81-4