Products 1792180-81-4

CAS 1792180-81-4 appears in our catalog under these names: Ritlecitinib, Ritlecitinib/ 99.92% (existing batch purity), PF–06651600, PF 06651600, Ritlecitinib 95%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 100mg, 10mg, 50mg, 2mg, 5mg, 25mg, 200mg, 500mg.

Structural formula: {0} (CAS {1})

Ritlecitinib is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a [(3R,6S)-6-methyl-1-(prop-2-enoyl)piperidin-3-yl]amino group. It is a dual inhibitor of Janus kinase 3 and the TEC family of tyrosine kinases. It has a role as an anti-inflammatory drug, an immunosuppressive agent, an antirheumatic drug, a dermatologic drug and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a tertiary carboxamide, a member of acrylamides, a pyrrolopyrimidine, a N-acylpiperidine and a secondary amino compound. It is a conjugate base of a ritlecitinib(1+).

Source: ChEBI

Identity
Molecular formulaC15H19N5O
Molecular weight285.34 g/mol
IUPAC name1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
InChIKeyCBRJPFGIXUFMTM-WDEREUQCSA-N
SMILESC[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3

Computed by PubChem (NCBI)