CAS 134678-17-4 appears in our catalog under these names: Lamivudine, 50 g, Lamivudine, Lamivudeine, Lamivudeine 100 µg/mL in Acetonitrile:Water, Lamivudine/ 99.56% (existing batch purity). Offered by: Roth, Chemat Brand, TRC, Mikromol, LoGiCal. Available pack sizes: 50g, on request, 100mg, 25mg, 50mg, 250mg, 10mg, 1ml.
Lamivudine is a monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B. It has a role as an antiviral drug, a prodrug, an allergen, a HIV-1 reverse transcriptase inhibitor, an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an anti-HBV agent. It is a primary alcohol, an oxacycle, a monothioacetal and a nucleoside analogue. It is functionally related to a cytosine.
Source: ChEBI
| Molecular formula | C8H11N3O3S |
|---|---|
| Molecular weight | 229.26 g/mol |
| IUPAC name | 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one |
| InChIKey | JTEGQNOMFQHVDC-NKWVEPMBSA-N |
| SMILES | C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N |
Computed by PubChem (NCBI)