Products 136891-12-8

CAS 136891-12-8 is the registry number for rac-cis-Lamivudine ((2RS,5SR)-Lamivudine). Offered by: Mikromol. Available pack sizes: 25mg.

Structural formula: {0} (CAS {1})

Lamivudine is a monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B. It has a role as an antiviral drug, a prodrug, an allergen, a HIV-1 reverse transcriptase inhibitor, an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an anti-HBV agent. It is a primary alcohol, an oxacycle, a monothioacetal and a nucleoside analogue. It is functionally related to a cytosine.

Source: ChEBI

Identity
Molecular formulaC8H11N3O3S
Molecular weight229.26 g/mol
IUPAC name4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
InChIKeyJTEGQNOMFQHVDC-NKWVEPMBSA-N
SMILESC1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N

Computed by PubChem (NCBI)