Products 30195-30-3
CAS 30195-30-3 appears in our catalog under these names: Ro 5-3335, 95%, Ro5-3335/ 99.95% (existing batch purity), Ro 5–3335, Ro 5-3335, >98.0%(HPLC), Ro 5-3335. Offered by: Combi-blocks, TargetMol, GLPBio, TCI, Biosynth. Available pack sizes: 50mg, 10mg, 1mg, 5mg, 25mg, 100mg, 50 mg, 10 mg.
Ro 5-3335 is a 1,4-benzodiazepinone that is nordazepam in which the phenyl substituent has been replaced by a 1H-pyrrol-2-yl group. It inhibits gene expression in HIV-1 at the transcriptional level through interference with Tat-mediated transactivation. It has a role as a RUNX1 inhibitor, a HIV-1 Tat inhibitor, an antineoplastic agent and an anti-HIV-1 agent. It is a member of pyrroles, a 1,4-benzodiazepinone and an organochlorine compound.
Source: ChEBI
| Molecular formula | C13H10ClN3O |
|---|---|
| Molecular weight | 259.69 g/mol |
| IUPAC name | 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-1,4-benzodiazepin-2-one |
| InChIKey | XWNMORIHKRROGW-UHFFFAOYSA-N |
| SMILES | C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CN3 |
Computed by PubChem (NCBI)
Synonyms:
Ro 5-3335, 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one, 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-, Ro5-3335, Ro-5-3335, 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-1,4-benzodiazepin-2-one, 7-chloro-5-(1H-pyrrol-2-yl)-1H-benzo[e][1,4]diazepin-2(3H)-one, 7-Chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one, 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-pyrrol-2-yl-, 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one