Products 86541-78-8
CAS 86541-78-8 appears in our catalog under these names: Benazeprilat, Benazeprilat, >95% (HPLC), (2S)-2-(((3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl)amino)-4-phenylbutanoic Acid (Benazeprilat), Benazeprilat/ 98.35% (existing batch purity), Benazeprilat 95%. Offered by: Chemat Brand, TRC, LoGiCal, Mikromol, TargetMol. Available pack sizes: on request, 10mg, 50mg, 5mg, 25mg, 1mg, 100mg, Get quote.
Benazeprilat is a benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino group of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It is a lactam, a benzazepine and a dicarboxylic acid.
Source: ChEBI
| Molecular formula | C22H24N2O5 |
|---|---|
| Molecular weight | 396.4 g/mol |
| IUPAC name | (2S)-2-[[(3S)-1-(carboxymethyl)-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]amino]-4-phenylbutanoic acid |
| InChIKey | MADRIHWFJGRSBP-ROUUACIJSA-N |
| SMILES | C1CC2=CC=CC=C2N(C(=O)[C@H]1N[C@@H](CCC3=CC=CC=C3)C(=O)O)CC(=O)O |
Computed by PubChem (NCBI)