(+)–Bicuculline

cas: 485-49-4 — see every product listed under this CAS number, including other names

(+)–Bicuculline (CAS 485-49-4) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.

brand	GLPBio
catalog number	GN10745-250
cas	485-49-4
size	250mg

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Available pack sizes

brand	size	price
GLPBio	250mg	1088.49 Pln
GLPBio	10mM (in 1ml dmso)	667.25 Pln
GLPBio	50mg	592.36 Pln

properties

purity	No data
delivery time	To be confirmed by Chemat

Bicuculline is a benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. It has a role as a GABAA receptor antagonist, an agrochemical, a central nervous system stimulant, a GABA-gated chloride channel antagonist and a neurotoxin. It is a benzylisoquinoline alkaloid, an isoquinoline alkaloid and a member of isoquinolines.

Source: ChEBI

Identity
Molecular formula	C₂₀H₁₇NO₆
Molecular weight	367.4 g/mol
IUPAC name	(6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
InChIKey	IYGYMKDQCDOMRE-ZWKOTPCHSA-N
SMILES	CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3

Computed by PubChem (NCBI)

Synonyms: bicuculline, d-Bicuculline, Bicculine, Bicucullin, (+)-Bicuculline, Bicuculline (+), D-Bic uculline, bicuculline-(+), IYGYMKDQCDOMRE-ZWKOTPCHSA-N, Bicuculline,(+)