(+)-Bicuculline, BioScience Grade, 50 mg

cas: 485-49-4 — see every product listed under this CAS number, including other names

(+)-Bicuculline, BioScience Grade, 50 mg (CAS 485-49-4) is a chemical reagent available from Chemat. Available pack sizes: 50mg. Offered by: Roth.

brand	Roth
catalog number	ROTH-28TX.1
cas	485-49-4
size	50mg

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Available pack sizes

brand	size	price
Roth	50mg	514.44 Pln

properties

delivery time	2 week

Bicuculline is a benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. It has a role as a GABAA receptor antagonist, an agrochemical, a central nervous system stimulant, a GABA-gated chloride channel antagonist and a neurotoxin. It is a benzylisoquinoline alkaloid, an isoquinoline alkaloid and a member of isoquinolines.

Source: ChEBI

Identity
Molecular formula	C₂₀H₁₇NO₆
Molecular weight	367.4 g/mol
IUPAC name	(6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
InChIKey	IYGYMKDQCDOMRE-ZWKOTPCHSA-N
SMILES	CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3

Computed by PubChem (NCBI)

Synonyms: bicuculline, d-Bicuculline, Bicculine, Bicucullin, (+)-Bicuculline, Bicuculline (+), D-Bic uculline, bicuculline-(+), IYGYMKDQCDOMRE-ZWKOTPCHSA-N, Bicuculline,(+)