(+)-Bicuculline, >98.0%(HPLC)(T)

cas: 485-49-4 — see every product listed under this CAS number, including other names

(+)-Bicuculline, >98.0%(HPLC)(T) (CAS 485-49-4) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 100mg. Offered by: TCI.

brandTCI
catalog numberB1890-25MG
cas485-49-4
size25mg
availability 2 tygodnie|2 weeks
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
TCI 25mg 385.37 Pln
TCI 100mg 872.17 Pln

properties

delivery time2 weeks
categorychemicals
purity>98.0%(HPLC)(T)
Structural formula: {0} (CAS {1})

Bicuculline is a benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. It has a role as a GABAA receptor antagonist, an agrochemical, a central nervous system stimulant, a GABA-gated chloride channel antagonist and a neurotoxin. It is a benzylisoquinoline alkaloid, an isoquinoline alkaloid and a member of isoquinolines.

Source: ChEBI

Identity
Molecular formulaC20H17NO6
Molecular weight367.4 g/mol
IUPAC name(6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
InChIKeyIYGYMKDQCDOMRE-ZWKOTPCHSA-N
SMILESCN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3

Computed by PubChem (NCBI)

Synonyms: bicuculline, d-Bicuculline, Bicculine, Bicucullin, (+)-Bicuculline, Bicuculline (+), D-Bic uculline, bicuculline-(+), IYGYMKDQCDOMRE-ZWKOTPCHSA-N, Bicuculline,(+)
Isomers (same molecular formula)
12-hydroxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-23-one C20H17NO6
(2S)-2-[[2-(4-methyl-2-oxochromen-7-yl)oxyacetyl]amino]-2-phenylacetic acid C20H17NO6
methyl 1-(acetyloxymethyl)-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate C20H17NO6
(2S)-2-(1,3-dioxoisoindol-2-yl)-5-oxo-5-phenylmethoxypentanoic acid C20H17NO6
9-acetyl-9-amino-6,7,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione C20H17NO6
6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-9H-[1,3]dioxolo[4,5-h]isochromene]-6'-one C20H17NO6
21-hydroxy-16,17-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(21),2,4(8),9,15(20),16,18-heptaen-14-one C20H17NO6
(5R,8'R)-8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one C20H17NO6

Also listed as

Bicuculline, >95% (HPLC) TRC CAS 485-49-4
Bicuculline LoGiCal CAS 485-49-4
(+)–Bicuculline GLPBio CAS 485-49-4
Bicuculline/ 99.99% TargetMol CAS 485-49-4
(+)-Bicuculline Biosynth CAS 485-49-4
(+)-Bicuculline - Bio-X â„¢ Biosynth CAS 485-49-4
Bicuculline, 99.97% MedChemExpress CAS 485-49-4
Bicuculline (Standard) MedChemExpress CAS 485-49-4
(+)-Bicuculline, BioScience Grade, 50 mg Roth CAS 485-49-4
(+)-BICUCULLINE, 98% Fluorochem CAS 485-49-4
(6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 99% Chemat CAS 485-49-4