(6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 99%

cas: 485-49-4 — see every product listed under this CAS number, including other names

(6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 99% (CAS 485-49-4) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 50mg, 100mg, 250mg, 1g. Offered by: Chemat.

brandChemat
catalog numberCh11DEFZ-1mg
cas485-49-4
size1mg
availability 5g
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Available pack sizes

brand size price
Chemat 1mg 88.40 Pln
Chemat 50mg 299.60 Pln
Chemat 100mg 438.80 Pln
Chemat 250mg 942.80 Pln
Chemat 1g 3002.00 Pln

properties

purity99%
delivery time3 weeks
Structural formula: {0} (CAS {1})

Bicuculline is a benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. It has a role as a GABAA receptor antagonist, an agrochemical, a central nervous system stimulant, a GABA-gated chloride channel antagonist and a neurotoxin. It is a benzylisoquinoline alkaloid, an isoquinoline alkaloid and a member of isoquinolines.

Source: ChEBI

Identity
Molecular formulaC20H17NO6
Molecular weight367.4 g/mol
IUPAC name(6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
InChIKeyIYGYMKDQCDOMRE-ZWKOTPCHSA-N
SMILESCN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3

Computed by PubChem (NCBI)

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