2-CHLORO-2'-DEOXYADENOSINE
cas: 4291-63-8 — see every product listed under this CAS number, including other names
2-CHLORO-2'-DEOXYADENOSINE (CAS 4291-63-8) is a chemical reagent available from Chemat. Available pack sizes: 10MG, 25MG. Offered by: Sigma-Aldrich.
| brand | Sigma-Aldrich |
|---|---|
| catalog number | C4438-10MG |
| cas | 4291-63-8 |
| size | 10MG |
| availability | availability |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Sigma-Aldrich | 10MG | 1370.00 Pln | |
| Sigma-Aldrich | 25MG | 2810.00 Pln |
properties
| purity | No data |
|---|---|
| delivery time | 1-2 weeks (only if in stock, to check click on availability) |
Cladribine is 2'-Deoxyadenosine in which the hydrogen at position 2 on the purine ring has been substituted by chlorine. It inhibits the synthesis and repair of DNA, particularly in lymphocytes and monocytes, and is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia. It has a role as an antineoplastic agent and an immunosuppressive agent. It is a purine 2'-deoxyribonucleoside and an organochlorine compound.
Source: ChEBI
| Molecular formula | C10H12ClN5O3 |
|---|---|
| Molecular weight | 285.69 g/mol |
| IUPAC name | (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol |
| InChIKey | PTOAARAWEBMLNO-KVQBGUIXSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O |
Computed by PubChem (NCBI)