Cladribine - Bio-X â„¢

cas: 4291-63-8 — see every product listed under this CAS number, including other names

Cladribine - Bio-X â„¢ (CAS 4291-63-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg. Offered by: Biosynth.

brandBiosynth
catalog numberBC164318-10mg
cas4291-63-8
size10mg
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Available pack sizes

brand size price
Biosynth 10mg price on request

properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Other Targets
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

Cladribine is 2'-Deoxyadenosine in which the hydrogen at position 2 on the purine ring has been substituted by chlorine. It inhibits the synthesis and repair of DNA, particularly in lymphocytes and monocytes, and is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia. It has a role as an antineoplastic agent and an immunosuppressive agent. It is a purine 2'-deoxyribonucleoside and an organochlorine compound.

Source: ChEBI

Identity
Molecular formulaC10H12ClN5O3
Molecular weight285.69 g/mol
IUPAC name(2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
InChIKeyPTOAARAWEBMLNO-KVQBGUIXSA-N
SMILESC1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O

Computed by PubChem (NCBI)

Synonyms: Cladribine, 2-Chloro-2'-deoxyadenosine, Leustatin, 2-Chlorodeoxyadenosine, 2-CdA, Chlorodeoxyadenosine, Litak, CldAdo, 2-Chloro-2'-deoxy-beta-adenosine, cladribina
Related forms of this compound
(2R,3S,5S)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol C10H12ClN5O3
Isomers (same molecular formula)
(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol C10H12ClN5O3
(2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(chloromethyl)oxolane-3,4-diol C10H12ClN5O3
(2S,3S,4R,5R)-2-(6-aminopurin-9-yl)-5-(chloromethyl)oxolane-3,4-diol C10H12ClN5O3
2-[(2-amino-6-chloropurin-9-yl)methoxy]ethyl acetate C10H12ClN5O3
(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-chloro-2-(hydroxymethyl)oxolan-3-ol C10H12ClN5O3
(2R,3S,5R)-5-(6-amino-8-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol C10H12ClN5O3
5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol C10H12ClN5O3
(2R,3R,5S)-2-(2-amino-6-chloropurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol C10H12ClN5O3
(2R,3R,5S)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol C10H12ClN5O3

Also listed as

Cladribine Chemat Brand CAS 4291-63-8
Cladribine, >95% (HPLC) TRC CAS 4291-63-8
Cladribine/ 99.87% (existing batch purity) TargetMol CAS 4291-63-8
Cladribine, >98.0%(HPLC) TCI CAS 4291-63-8
2-CHLORO-2'-DEOXYADENOSINE Sigma-Aldrich CAS 4291-63-8
2-Chloro-2′-deoxyadenosine 1PC X 10MG Sigma-Aldrich CAS 4291-63-8
Cladribine, BioScience Grade, 10 mg Roth CAS 4291-63-8
Cladribine, 99.96% MedChemExpress CAS 4291-63-8
Cladribine (Standard) MedChemExpress CAS 4291-63-8
2-Chloro-2'-deoxyadenosine, 98% Fluorochem CAS 4291-63-8
Cladribine, 98% Ambeed CAS 4291-63-8