Gilteritinib 97%

cas: 1254053-43-4 — see every product listed under this CAS number, including other names

Gilteritinib 97% (CAS 1254053-43-4) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 50mg, 100mg, 250mg, 1g. Offered by: Ambeed.

brandAmbeed
catalog numberA425350-1mg
cas1254053-43-4
size1mg
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Ambeed 1mg 147.88 Pln
Ambeed 2mg 175.69 Pln
Ambeed 5mg 203.50 Pln
Ambeed 10mg 231.31 Pln
Ambeed 50mg 286.94 Pln
Ambeed 100mg 392.62 Pln
Ambeed 250mg 642.94 Pln
Ambeed 1g 1377.19 Pln
Ambeed 5g 4214.06 Pln

properties

purity97%
delivery time 1-2 weeks
ambeed catalog no.A425350
Structural formula: {0} (CAS {1})

Gilteritinib is a member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a primary carboxamide, a monomethoxybenzene, a member of piperidines, an aromatic amine, a member of pyrazines, a N-methylpiperazine, a member of oxanes and a secondary amino compound.

Source: ChEBI

Identity
Molecular formulaC29H44N8O3
Molecular weight552.7 g/mol
IUPAC name6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
InChIKeyGYQYAJJFPNQOOW-UHFFFAOYSA-N
SMILESCCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5

Computed by PubChem (NCBI)

Synonyms: Gilteritinib, gilteritinibum, Gilteritinib HCl, Gilteritinib [USAN:INN], Gilteritinib (Standard), GILTERITINIB [MI], Gilteritinib(ASP2215), Gilteritinib (USAN/INN), GILTERITINIB [INN], GILTERITINIB [USAN]
Related forms of this compound
6-ethyl-3-[3-methoxy-4-[4-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide C29H44N8O3

Also listed as

6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide, 97%, 97% Chemat CAS 1254053-43-4
Gilteritinib Chemat Brand CAS 1254053-43-4
Gilteritinib, >95% (HPLC) TRC CAS 1254053-43-4
Gilteritinib/ 99.72% (existing batch purity) TargetMol CAS 1254053-43-4
Gilteritinib, 98% Thermo Scientific (Acros) CAS 1254053-43-4
Gilteritinib, 99.84% MedChemExpress CAS 1254053-43-4
Gilteritinib (Standard), 99.60% MedChemExpress CAS 1254053-43-4
Gilteritinib, 97% Fluorochem CAS 1254053-43-4