cas: 404950-80-7 — see every product listed under this CAS number, including other names
Panobinostat, >93.0%(HPLC) (CAS 404950-80-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg. Offered by: TCI.
| brand | TCI |
|---|---|
| catalog number | P3137-10MG |
| cas | 404950-80-7 |
| size | 10mg |
| availability | 2 tygodnie|2 weeks |
| brand | size | price | |
|---|---|---|---|
| TCI | 10mg | 321.44 Pln |
| delivery time | 2 weeks |
|---|---|
| category | chemicals |
| purity | >93.0%(HPLC) |
Panobinostat is a hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma. It has a role as an antineoplastic agent, an angiogenesis modulating agent and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a member of cinnamamides, a hydroxamic acid, a methylindole and a secondary amino compound. It is a conjugate base of a panobinostat(1+).
Source: ChEBI
| Molecular formula | C21H23N3O2 |
|---|---|
| Molecular weight | 349.4 g/mol |
| IUPAC name | (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide |
| InChIKey | FPOHNWQLNRZRFC-ZHACJKMWSA-N |
| SMILES | CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO |
Computed by PubChem (NCBI)