Panobinostat

cas: 404950-80-7 — see every product listed under this CAS number, including other names

Panobinostat (CAS 404950-80-7) is a chemical reagent available from Chemat. Available pack sizes: on request, 0,25g, 0,5g, 1g, 250MG, 10g, 5g. Offered by: Chemat Brand, Biosynth, Thermo Scientific (Acros).

brandChemat Brand
catalog numberULP841
cas404950-80-7
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat

Available pack sizes

brand size price
Chemat Brand on request price on request
Biosynth 0,25g price on request
Biosynth 0,5g price on request
Thermo Scientific (Acros) 1g 2316.31 Pln
Thermo Scientific (Acros) 250MG 775.07 Pln
Biosynth 1g price on request
Biosynth 10g price on request
Biosynth 5g price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat

Panobinostat is a hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma. It has a role as an antineoplastic agent, an angiogenesis modulating agent and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a member of cinnamamides, a hydroxamic acid, a methylindole and a secondary amino compound. It is a conjugate base of a panobinostat(1+).

Source: ChEBI

Identity
Molecular formulaC21H23N3O2
Molecular weight349.4 g/mol
IUPAC name(E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide
InChIKeyFPOHNWQLNRZRFC-ZHACJKMWSA-N
SMILESCC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO

Computed by PubChem (NCBI)

Also listed as