cas: 404950-80-7 — see every product listed under this CAS number, including other names
Panobinostat (LBH589) (CAS 404950-80-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 200mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC12257-10 |
| cas | 404950-80-7 |
| size | 10mg |
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 629.80 Pln | |
| GLPBio | 200mg | 1327.20 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 625.12 Pln | |
| GLPBio | 50mg | 854.47 Pln | |
| GLPBio | 500mg | 2015.23 Pln |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Panobinostat is a hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma. It has a role as an antineoplastic agent, an angiogenesis modulating agent and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a member of cinnamamides, a hydroxamic acid, a methylindole and a secondary amino compound. It is a conjugate base of a panobinostat(1+).
Source: ChEBI
| Molecular formula | C21H23N3O2 |
|---|---|
| Molecular weight | 349.4 g/mol |
| IUPAC name | (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide |
| InChIKey | FPOHNWQLNRZRFC-ZHACJKMWSA-N |
| SMILES | CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO |
Computed by PubChem (NCBI)