Products 191471-52-0
CAS 191471-52-0 appears in our catalog under these names: LY 379268, LY379268, 98%, LY 379268, LY379268, 99%, 99%, LY379268, 99.84%. Offered by: TRC, AmBeed, GLPBio, Biosynth, Chemat. Available pack sizes: 500mg, 250mg, 100mg, 1mg, 10mg, 5mg, 2mg, 25mg.
LY 379268 is an organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia. It has a role as an anxiolytic drug, an antipsychotic agent, a metabotropic glutamate receptor agonist and a neuroprotective agent. It is an organic heterobicyclic compound, a bridged compound and an amino dicarboxylic acid.
Source: ChEBI
| Molecular formula | C7H9NO5 |
|---|---|
| Molecular weight | 187.15 g/mol |
| IUPAC name | (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid |
| InChIKey | YASVRZWVUGJELU-MDASVERJSA-N |
| SMILES | C1[C@]([C@@H]2[C@H]([C@@H]2O1)C(=O)O)(C(=O)O)N |
Computed by PubChem (NCBI)
Synonyms:
(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, (1R,4R,5S,6R)-4-Amino-2-oxabicyclo(3.1.0)hexane-4,6-dicarboxylic acid, 2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, 4-amino-, (1R,4R,5S,6R)-, (1S,2R,5R,6R)-2-amino-4-oxabicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-Oxabicyclo(3.1.0)hexane-4,6-dicarboxylic acid, 4-amino-, (1R,4R,5S,6R)-, 2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid,4-amino-,(1R,4R,5S,6R)-rel-, 4-Amino-2-oxa-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid, (1R,4R,5S,6R)-4-Amino-2-oxa-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid