Products 364-98-7

CAS 364-98-7 appears in our catalog under these names: Diazoxide, 98%, 98%, Diazoxide, 98% , Diazoxide, Diazoxide, >95% (HPLC), Diazoxide/ 100%. Offered by: Chemat, Thermo Scientific (Alfa Aesar), Chemat Brand, TRC, Mikromol. Available pack sizes: 100mg, 250mg, 1g, 5g, 10g, 25g, 500mg, on request.

Structural formula: {0} (CAS {1})

Diazoxide is a benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. It has a role as a diuretic, a beta-adrenergic agonist, a bronchodilator agent, a sympathomimetic agent, a vasodilator agent, an antihypertensive agent, a cardiotonic drug, a sodium channel blocker and a K-ATP channel agonist. It is a sulfone, an organochlorine compound and a benzothiadiazine.

Source: ChEBI

Identity
Molecular formulaC8H7ClN2O2S
Molecular weight230.67 g/mol
IUPAC name7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
InChIKeyGDLBFKVLRPITMI-UHFFFAOYSA-N
SMILESCC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl

Computed by PubChem (NCBI)