Products 18000-24-3
CAS 18000-24-3 appears in our catalog under these names: 7-Chlorokynurenic acid, 95%, 7-Chlorokynurenic acid, 7-Chlorokynurenic acid/ 99.72% (existing batch purity), 7–Chlorokynurenic acid, 7-Chlorokynurenic acid, 98+% . Offered by: Combi-blocks, TRC, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar). Available pack sizes: 5g, 10g, 1g, 250mg, 10mg, 25mg, 5mg, 50mg.
7-chlorokynurenic acid is a quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid. It has a role as a NMDA receptor antagonist and a neuroprotective agent. It is a quinolinemonocarboxylic acid and an organochlorine compound.
Source: ChEBI
| Molecular formula | C10H6ClNO3 |
|---|---|
| Molecular weight | 223.61 g/mol |
| IUPAC name | 7-chloro-4-oxo-1H-quinoline-2-carboxylic acid |
| InChIKey | UAWVRVFHMOSAPU-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1Cl)NC(=CC2=O)C(=O)O |
Computed by PubChem (NCBI)
Synonyms:
7-Chlorokynurenic acid, 7-chloro-4-oxo-1H-quinoline-2-carboxylic acid, Kynurenic acid, 7-chloro-, 7-Chloro-4-hydroxyquinoline-2-carboxylic acid, 7-Chloro-kynurenic acid, 2-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, 7-Cl-KYNA, 7-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid, 7-chloro-4-hydroxy-2-carboxyquinoline, 7-chlorokynurenic-acid